Publications Category

Predicting Empathy From Resting State Brain Connectivity: A Multivariate Approach

predicting trait empathy

Published in Frontiers in Integrative Neuroscience Abstract: Recent task fMRI studies suggest that individual differences in trait empathy and empathic concern are mediated by patterns of connectivity between self-other resonance and top-down control networks that are stable across task demands. An untested implication of this hypothesis is that these stable patterns of connectivity should be […]

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The Method of Loci in Virtual Reality: Explicit Binding of Objects to Spatial Contexts Enhances Subsequent Memory Recall

The Method of Loci in Virtual Reality: Explicit Binding of Objects to Spatial Contexts Enhances Subsequent Memory Recall Figure

Abstract The method of loci (MoL) is a well-known mnemonic technique in which visuospatial spatial environments are used to scaffold the memorization of non-spatial information. We developed a novel virtual reality-based implementation of the MoL in which participants used three unique virtual environments to serve as their “memory palaces.” In each world, participants were presented […]

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Enhancing the Ecological Validity of fMRI Memory Research Using Virtual Reality

Authors: Nicco Reggente, Joey K.Y. Essoe, Zahra M. Aghajan, Amir V. Tavakoli, Joseph F. McGuire, Nanthia A. Suthana, Jesse Rissman Article: PDF Plain English: Functional magnetic resonance imaging (fMRI) is a powerful research tool to understand the neural underpinnings of human memory. However, as memory is known to be context-dependent, differences in contexts between naturalistic settings […]

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Memory Recall for High Reward Value Items Correlates With Individual Differences in White Matter Pathways Associated With Reward Processing and Fronto-Temporal Communication

Authors: Nicco Reggente, Michael S. Cohen, (Amy) Zhong S. Zheng, Alan D. Castel, Barbara J. Knowlton, Jesse Rissman Article: PDF Plain English: We observed individual differences in a value-directed remembering task. White matter integrity within the Uncinate Fasciculus correlated with memory strength for high-value items. This relationship was also seen for the tract connecting the […]

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Multivariate resting-state functional connectivity predicts response to cognitive behavioral therapy in obsessive – compulsive disorder

Authors: Nicco Reggente, Teena D. Moody, Francesca Morfini, Courtney Sheen, Jesse Rissman, Joseph O’Neill and Jamie D. Feusner Article: PDF | Supporting Information Plain English: In this work, we collected Resting-State fMRI data from patients with OCD before they engaged in 4 weeks of Cognitive Behavioral Therapy (CBT). We calculated functional connectivity within the Default […]

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Shared and distinct contributions of rostrolateral prefrontal cortex to analogical reasoning and episodic memory retrieval

Andrew Westphal, Nicco Reggente, Kaori Ito, Jesse Rissman Abstract: Rostrolateral prefrontal cortex (RLPFC) is widely appreciated to support higher cognitive functions, including analogical reasoning and episodic memory retrieval. However, these tasks have typically been studied in isolation, and thus it is unclear whether they involve common or distinct RLPFC mechanisms. Here, we introduce a novel […]

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Decoding fMRI Signatures of Real-world Autobiographical Memory Retrieval

Jesse Rissman, Tiffany E. Chow, Nicco Reggente, and Anthony D. Wagner Abstract: Extant neuroimaging data implicate frontoparietal and medial-temporal lobe regions in episodic retrieval, and the specific pattern of activity within and across these regions is diagnostic of an individual’s subjective mnemonic experience. For example, in laboratory-based paradigms, memories for recently encoded faces can be […]

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Individual differences in working memory performance as a function of the local integrity and regional connectivity of the hippocampus

Kommers, C.,, Reggente, N., Raccah, O., Rissman, J. Cody Kommers, my research assistant, presented this poster at SfN in Washington, D.C (2014) SfN 2014 Poster SfN 2014 Abstract: Although the hippocampus is well known to contribute to the storage and retrieval of long-term memories, emerging data suggests that the hippocampus may also contribute to the […]

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Predicting individual differences in cognitive gains from videogame training using machine learning analyses of fMRI functional connectivity patterns

CNS 2014 Abstract: Nikolaidis, A., Reggente, N. et al Summary: Using the the task-dependent functional connectivity across nodes within established cortical network from both before and after videogame training, we were able to asses the “plasticity” of these networks as a function of training. The plasticity of these networks, combined with graph theoretical metrics were […]

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Disentangling Disorders of Consciousnes: Insights from DTI and MVPA

CNS 2014 Poster: Zheng, Z., Reggente, N. et al. CNS 2014 Summary: For this poster we used Diffusion Tensor Imaging (DTI) techniques to compute thalamo-cortical probabilistic tractography maps. That is, for every voxel in the Thalamus, we determined every other voxel in the brain’s probabilist structural connectivity with that voxel. We did this for a […]

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