Neuroscience Category
Multivariate resting-state functional connectivity predicts response to cognitive behavioral therapy in obsessive – compulsive disorder
Posted on February 13, 2018

Authors: Nicco Reggente, Teena D. Moody, Francesca Morfini, Courtney Sheen, Jesse Rissman, Joseph O’Neill and Jamie D. Feusner Article: PDF | Supporting Information Plain English: In this work, we collected Resting-State fMRI data from patients with OCD before they engaged in 4 weeks of Cognitive Behavioral Therapy (CBT). We calculated functional connectivity within the Default […]
The Method of Loci revisited: Virtually augmented memory palaces [ICPS 2017 Symposium Presentation]
Posted on April 19, 2017 Leave a Comment

Symposium talk presented at ICPS 2017 in Vienna, Austria Abstract: Humans have long appreciated that visuospatial cues can serve as a scaffolding for the encoding of non-spatial content. The Method of Loci (MoL), which binds objects to a spatial context in one’s mental imagery, has helped enhance the mnemonic retrieval processes of memory champions since Ancient […]
Prediction of response to cognitive-behavioral therapy in obsessive-compulsive disorder: a multivariate analysis of resting state functional connectivity
Posted on December 8, 2016 Leave a Comment
Jamie D Feusner, MD1; Nicco Reggente, MA2; Teena D Moody, PhD1; Francesca Morfini, MA1; Jesse Rissman, PhD1,2; Joseph O’Neill, PhD1 Affiliation: 1Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, California 2Department of Psychology, UCLA, Los Angeles, California Background: Cognitive-behavioral therapy (CBT) is an effective treatment for reducing symptoms of […]
The Method of Loci revisited: Memory enhancement by way of virtually augmented memory palaces
Posted on December 8, 2016 Leave a Comment
Reggente, N., Essoe, J., Mehta, P.*, Ohno, A.*, Rissman, J. Humans have long appreciated that visuospatial cues can serve as a scaffolding for the encoding of non-spatial content. The Method of Loci (MoL), which binds objects to a spatial context in one’s mental imagery, has been the favored mnemonic strategy of memory champions since Ancient Greece. […]
Neural correlates of fluid intelligence via functional and structural network connectivity measures
Posted on December 8, 2016 Leave a Comment
Connectivity across regions in the brain can be characterized as either functional (correlated fluctuations in activity as measured by resting-state fMRI data) or structural (white matter pathways as measured by diffusion MRI data). Emerging studies suggest that the connections across brain regions that make up distinct cognitive networks can partially explain individual differences in behavioral […]
Disentangling Disorders of Consciousness: Insights from Diffusion Tensor Imaging and Machine Learning
Posted on September 6, 2016 Leave a Comment
Abstract: Previous studies have suggested that disorders of consciousness (DOC) after severe brain injury may result from disconnections of the thalamo-cortical system. However, thalamo-cortical connectivity differences between vegetative state (VS), minimally conscious state minus (MCS-,i.e., low-level behavior such as visual pursuit), and minimally conscious state plus (MCS+, i.e., high-level behavior such as language processing) remain unclear. […]
Mapping neural representations of heading direction and environmental context during imagined navigation of learned virtual environments
Posted on April 7, 2016 Leave a Comment

Authors: Nicco Reggente., Essoe, J.K., Jevtic, I., Rissman, J. Abstract for CNS 2016 in New York, NY: Constructing a rich egocentric representation of one’s movement about an environment is a multi-faceted effort requiring a vast interplay across cortical areas responsible for visual processing, heading direction, and spatial coding. While electrophysiological recordings in rodents have identified […]
Shared and distinct contributions of rostrolateral prefrontal cortex to analogical reasoning and episodic memory retrieval
Posted on January 20, 2016 Leave a Comment
Andrew Westphal, Nicco Reggente, Kaori Ito, Jesse Rissman Abstract: Rostrolateral prefrontal cortex (RLPFC) is widely appreciated to support higher cognitive functions, including analogical reasoning and episodic memory retrieval. However, these tasks have typically been studied in isolation, and thus it is unclear whether they involve common or distinct RLPFC mechanisms. Here, we introduce a novel […]
Thinking with space: How mental representations of space bolster cognitive processes
Posted on July 12, 2015 3 Comments
The concept of thinking with space may seem as ubiquitously obvious as the answer to the question posed by David Foster Wallace’s (2009) fictional fish: “what is water”? For, how would it be possible to do anything without space? Of course we think with space; we exist in space, neurons take up space, and […]
Decoding the contents of perceived and imagined navigation through virtual reality environments
Posted on June 15, 2015 Leave a Comment
Reggente, N., Essoe, J.K., Jevtic, I., Rissman, J. This poster was presented under the Higher Cognitive Functions: Space, Time, and Number Coding category at the Organization for Human Brain Mapping Annual Conference in Honolulu, Hawaii on Monday June 15, 2015 See the full poster here: Reggente_OHBM_Final Introduction: Navigating about one’s environment is a multi-faceted effort […]